Reference

General Data I/O

IQRloadCSVdata()

Simple auxiliary to load a CSV dataset

IQRloadSASdata()

Loading SAS data

IQRoutputCSV()

Exporting a data.frame as CSV file

IQRoutputXPT()

Export general data.frame object as XPT file

IQRsaveCSVdata()

Simple auxiliary to save a CSV dataset with attributes

Help & Documentation

doc_IQnca()

Open IQnca documentation in browser

examples_IQnca()

Install examples to allow running examples from the book

install_MIDDmodule()

Installs defined webinar module from the web

install_workshop()

Installs workshop material

support()

Open support webpage

Installation

setup_IQnca()

Opening the setup_options_IQnca.R file for editing

NCA Data

IQdataNCA()

Create an IQdataNCA object

check_IQdataNCA()

Check IQdataNCA

dataSpec_IQdataNCA()

Show NCA data specification and display as a table

exportADNCA_IQdataNCA()

Export an IQdataNCA object to an ADNCA dataset

export_IQdataNCA()

Export an IQdataNCA object

ignoreNCA_IQdataNCA()

Define records to be excluded from NCA PK parameter determination

ignoreSUM_IQdataNCA()

Define records to be excluded from summary and inferential procedures

ignorerecord_IQdataNCA()

Define records to be ignored with reason why

ignoresubject_IQdataNCA()

Define subjects to be ignored for analyses with reason why

load_IQdataNCA()

Load an IQdataNCA object from CSV

plot(<IQdataNCA>)

Generic plot function for IQdataNCA objects

reportIgnoredSUMNCA_IQdataNCA()

Report ignored records from summary tables and/or NCA parameter determination

summaryObservations_IQdataNCA()

Table summarizing the available observations

NCA Data Figures

figure_spaghetti_IQdataNCA()

Plot summary spaghetti plots of IQdataNCA objects (non-dose-normalized)

figure_spaghetti_dosenorm_IQdataNCA()

Plot dose-normalized summary spaghetti plots of IQdataNCA objects

figure_summary_geomean_IQdataNCA()

Plot of summary PK concentrations (geometric mean and 95% CI)

figure_summary_geommean_dosenorm_IQdataNCA()

Plot of summary dose-normalized PK concentrations (geometric mean and 95% CI)

figure_summary_mean_IQdataNCA()

Plot of summary PK concentrations (arithmetic mean and SD)

figure_summary_mean_dosenorm_IQdataNCA()

Plot of summary dose-normalized PK concentrations (arithmetic mean and SD)

figures_indiv_IQdataNCA()

Generate individual PK concentration figures for reporting

plot_summary_IQdataNCAsum()

Generate one page with summary figure

NCA Data Listings

listing_conc_IQdataNCA()

Generate a simple listing of individual pharmacokinetic concentrations

listing_concdetailed_IQdataNCA()

Generate a detailed listing of individual pharmacokinetic concentrations

listing_ignoredSubjectsRecords_IQdataNCA()

Listing of ignored subjects and records

listing_time_IQdataNCA()

Generate a listing of individual pharmacokinetic concentration sampling times

listing_timedetailed_IQdataNCA()

Generate a listing of individual pharmacokinetic concentration sampling times

NCA Data Tables

table_summary_conc_IQdataNCA()

Generate a table of statistical summaries of pharmacokinetic concentrations

table_summary_conc_by_time_IQdataNCA()

Generate another table of statistical summaries of pharmacokinetic concentrations

NCA Parameter

paramSpec_IQnca()

Show NCA parameter specification and display as a table

NCA Parameter Export

exportCDISC_IQnca()

Export an IQnca object to CDISC PP and ADPP

export_IQnca()

Export an IQnca object

mutate_IQnca()

Modify or add columns (PK parameters) to the NCA result

NCA Parameter Listings

listing_pkparameter_IQnca()

Generate a listing of calculated PK parameters

mutate_IQnca()

Modify or add columns (PK parameters) to the NCA result

NCA Parameter Tables

mutate_IQnca()

Modify or add columns (PK parameters) to the NCA result

reliabilityTable_IQnca()

Determine reliability of the NCA results from IQnca object

table_summary_acrossGROUP_pkparameters_IQnca()

Generate a summary table for PK parameters (across dose groups)

table_summary_byGROUP_pkparameters_IQnca()

Generate a summary table for PK parameters (by dose group)

NCA Report

report_IQnca()

Generate default NCA report

NCA Slope

slope_IQdataNCA()

Slope calculation function for IQdataNCA objects

slope_manual_NCA()

Define slope points in subjects to be used for manual slope calculation

slopetest_IQnca()

Calculation of R2 and R2ADJ for slope of profile

Output & Compliance

IQRinitCompliance()

Initializes the compliance mode

IQRoutputCSV()

Exporting a data.frame as CSV file

IQRoutputFigure()

Create IQRoutputFigure object and/or print graph object to file

IQRoutputFile()

Exporting a text file with added compliance information log file

IQRoutputPDF()

Printing ggplot object or list of objects to a PDF file with added compliance information log file

IQRoutputPDFend()

Ends export to PDF (deprecated)

IQRoutputPDFstart()

Start export to PDF (deprecated)

IQRoutputPNG()

Printing a single ggplot object to png file with added compliance information log file

IQRoutputRDS()

Exporting an R object to RDS format with added compliance information log file

IQRoutputTable()

Convert dataframe to IQRoutputTable object and allow export

IQRoutputValueTable()

Exporting a value with label and potential description for reporting

IQRoutputXPT()

Export general data.frame object as XPT file

TLF customized

figure_indivConc_IQdataNCA()

Generate individual PK concentration figures for reporting

figure_lines_IQdataNCA()

Generate line figures of PK concentration for reporting

figure_summary_IQdataNCA()

Generate summary figures of PK concentration for reporting

listing_PKconc_IQdataNCA()

Generate a detailed listing of individual pharmacokinetic concentrations

listing_PKpars_IQnca()

Generate a detailed listing of individual pharmacokinetic parameters

table_summary_PKconc_IQdataNCA()

Generate a table of statistical summaries of pharmacokinetic concentrations

table_summary_PKpars_IQnca()

Generate a table of statistical summaries of pharmacokinetic parameters

write_IQncaFigure()

Function to plot IQncaFigure

Unassigned

AUC_IQnca()

AUC calculation

IQReport()

Interface to the IQReport command line interface tool

aux_plotlayout()

Determine layout for distribution single plots to rows, columns, and pages

createPages_IQRoutputFigure()

Create pages from IQRoutputFigure

date2dateday_IQRdataProgramming()

Conversion of date/time in string format to day in string format

date2datetime_IQRdataProgramming()

Conversion of date/time in string format to time in string format

date2time_IQRdataProgramming()

Conversion of date/time in string format to numeric values

geocv()

geometric CV auxiliary

geomean()

geometric mean auxiliary

geosd()

geometric sd auxiliary

getLabels_dataframe()

Extract label information of columns in data.frames

intervalAUC_NCA()

Define interval AUC calculation

nca_IQdataNCA()

Calculation of NCA PK parameters

print(<IQdataNCA>)

Generic print function for IQdataNCA objects

print(<IQnca>)

Generic print function for IQnca objects

removeCommata_dataframe()

Remove commata in elements in data.frame

scale_y_log10_IQnca() scale_x_log10_IQnca()

Log scale for x or y axis with proper grid lines

summary(<IQdataNCA>)

Generic summary function for IQdataNCA objects

unlabel_dataframe()

Remove labelled class and label